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PRNP 抗体

The 兔 单克隆 anti-PRNP antibody (Clone 33A5) (ABIN6944654) specifically detects PRNP in WB, IHC, IF (cc) 和 FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6944654
发货至: 中国
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Quick Overview for PRNP 抗体 (ABIN6944654)

抗原

See all PRNP 抗体
PRNP (Prion Protein (PRNP))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This PRNP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)

克隆位点

33A5
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    C terminal human Prion protein

    亚型

    IgG
  • 应用备注

    WB(1:300-1000), FCM(1:20-100), IF(ICC)(1:50-200), IHC()

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    PRNP (Prion Protein (PRNP))

    别名

    Prion Protein (PrP)

    背景

    Synonyms: Major prion protein, ASCR, PrP27-30, PrP33-35C, CD_antigen: CD230, PrP, PRNP

    Background: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

    基因ID

    5621

    UniProt

    P04156

    途径

    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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