HIST1H4A 抗体 (acLys16)
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北京 101111
Quick Overview for HIST1H4A 抗体 (acLys16) (ABIN6946913)
抗原
See all HIST1H4A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- acLys16
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic peptide corresponding to human histone H4 (acetyl K16).
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亚型
- IgG
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anti-Histone Cluster 1, H4a (HIST1H4A) (meLys20) antibody
HIST1H4A 适用: 人 ELISA, WB, IHC, FACS, DB 宿主: 兔 Polyclonal unconjugated
anti-Histone Cluster 1, H4a (HIST1H4A) (H4K16ac) antibodyHIST1H4A 适用: 人 ELISA, WB, IF, ChIP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Cluster 1, H4a (HIST1H4A) (H4K31ac) antibodyHIST1H4A 适用: 人 ELISA, WB, IF, ChIP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Cluster 1, H4a (HIST1H4A) (H4K12ac) antibodyHIST1H4A 适用: 人 ELISA, IF, ChIP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Cluster 1, H4a (HIST1H4A) (H4K8ac) antibodyHIST1H4A 适用: 人 ELISA, IF, ChIP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Cluster 1, H4a (HIST1H4A) (H4K79ac) antibodyHIST1H4A 适用: 人 ELISA, IF, ChIP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Histone Cluster 1, H4a (HIST1H4A) (2meLys20), (AA 1-30) antibodyHIST1H4A 适用: 人 WB, FACS, DB, IHC (p) 宿主: 兔 Polyclonal RB17115 unconjugated
anti-Histone Cluster 1, H4a (HIST1H4A) (AA 1-12) antibodyHIST1H4A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Cluster 1, H4a (HIST1H4A) (AA 10-22) antibodyHIST1H4A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Cluster 1, H4a (HIST1H4A) (AA 74-85) antibodyHIST1H4A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- HIST1H4A (Histone Cluster 1, H4a (HIST1H4A))
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别名
- HIST1H4A
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背景
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Synonyms: Histone H4, HIST1H4A, acetyl-Histone H4 (Lys16), H4K16Ac, histone cluster 4 H4, Histone H4 Acetylated on Lysine 16, H4 histone family
Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Histone H4 are known to be acetylated on Lysine 5, 8, 12, and 16. Acetylations are important for the regulation of histone deposition, transcriptional activation, DNA replication and repair. Hyper-acetylation of the histone tails is shown to neutralize positive charge and weakens histone-DNA and nucleosome-nucleosome interactions that destabilizes chromatin structure and increases the accessibility of DNA to various DNA-binding proteins.
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基因ID
- 121504
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UniProt
- P62805
抗原
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