WNK1 抗体
Quick Overview for WNK1 抗体 (ABIN6945392)
抗原
See all WNK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic peptide within Human WNK1 aa 100-200 (Cysteine residue).
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亚型
- IgG
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anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (pThr60) antibody
WNK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (AA 1-207) antibodyWNK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (N-Term) antibodyWNK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (AA 1154-1195), (Middle Region) antibodyWNK1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (AA 1954-2231) antibodyWNK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (C-Term) antibodyWNK1 适用: 人, 小鼠, 大鼠, 马, 猴, 兔, Bat, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (Internal Region) antibodyWNK1 适用: 人, 小鼠, 大鼠, 马, 猴, 兔, Pig, Bat, Hamster, 小鸡, Cow ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (AA 1-210) antibodyWNK1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (pThr60) antibodyWNK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WNK Lysine Deficient Protein Kinase 1 (WNK1) (AA 1848-1882) antibodyWNK1 适用: 人 WB 宿主: 兔 Polyclonal RB56242 unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))
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别名
- WNK1
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背景
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Synonyms: Serine/threonine-protein kinase WNK1, Erythrocyte 65 kDa protein, Kinase deficient protein, Protein kinase lysine-deficient 1, Protein kinase with no lysine 1, p65, hWNK1, WNK1, HSN2, KDP, KIAA0344, PRKWNK1
Background: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L. Acts as a scaffold to inhibit SLC4A4, SLC26A6 as well as CFTR activities and surface expression, recruits STK39 which mediates the inhibition.
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基因ID
- 65125
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UniProt
- Q9H4A3
抗原
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