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WT1 抗体

This anti-WT1 antibody is a 兔 单克隆 antibody detecting WT1 in IHC, FACS, WB, IHC (p) 和 IF (cc). Suitable for 人 和 小鼠.
产品编号 ABIN6945391
发货至: 中国

Quick Overview for WT1 抗体 (ABIN6945391)

抗原

See all WT1 抗体
WT1 (Wilms Tumor 1 (WT1))

适用

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人, 小鼠

宿主

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克隆类型

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单克隆

标记

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This WT1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

9G6
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Human Wilms Tumor Protein between 50 to 250 amino acids

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    WT1 (Wilms Tumor 1 (WT1))

    别名

    Wilms Tumor Protein

    背景

    Synonyms: Wilms tumor protein, WT33, WT1

    Background: Transcription factor that plays an important role in cellular development and cell survival (PubMed:7862533). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (PubMed:7862533, PubMed:17716689, PubMed:25258363). Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors (PubMed:15520190). Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing (PubMed:16934801). Isoform 1 has lower affinity for DNA, and can bind RNA (PubMed:19123921).

    基因ID

    7490

    UniProt

    P19544

    途径

    Tube Formation
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