VPS26A 抗体
Quick Overview for VPS26A 抗体 (ABIN6945309)
抗原
See all VPS26A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within human VPS26 aa 250 to the C-terminus
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亚型
- IgG
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anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (AA 228-327) antibody
VPS26A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C4 unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (C-Term) antibodyVerified VPS26A 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (AA 21-180) antibodyVPS26A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) antibodyVPS26A 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (AA 208-327) antibodyVPS26A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (C-Term) antibodyVPS26A 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (AA 263-291) antibodyVPS26A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22339 unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) antibodyVPS26A 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) antibodyVPS26A 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting-Associated Protein 26A (VPS26A) (AA 1-327) antibodyVPS26A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IP(1-2 μg)
IHC() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 12 months
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- VPS26A (Vacuolar Protein Sorting-Associated Protein 26A (VPS26A))
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别名
- VPS26A
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背景
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Synonyms: Vacuolar protein sorting-associated protein 26A, Vesicle protein sorting 26A, hVPS26, VPS26A, VPS26.
Background: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. Required for retrograde transport of lysosomal enzyme receptor IGF2R. Required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Required for the endosomal localization of WASHC2A (indicative for the WASH complex). Required for the endosomal localization of TBC1D5. Mediates retromer cargo recognition of SORL1 and is involved in trafficking of SORL1 implicated in sorting and processing of APP. Involved in retromer-independent lysosomal sorting of F2R. Involved in recycling of ADRB2. Enhances the affinity of SNX27 for PDZ-binding motifs in cargo proteins.
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基因ID
- 9559
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UniProt
- O75436
抗原
-
