Versican 抗体
Quick Overview for Versican 抗体 (ABIN6945282)
抗原
See all Versican (Vcan) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within human Versican aa 3100-3300
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亚型
- IgG
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anti-Versican (Vcan) (AA 3301-3396) antibody
Vcan 适用: 小鼠, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Versican (Vcan) (AA 3058-3299) antibodyVcan 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Versican (Vcan) antibodyVcan 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Versican (Vcan) (AA 2958-3209) antibodyVcan 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Versican (Vcan) (AA 362-585) antibodyVcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 unconjugated
anti-Versican (Vcan) (AA 362-585) antibody (HRP)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 HRP
anti-Versican (Vcan) (AA 362-585) antibody (FITC)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 FITC
anti-Versican (Vcan) (AA 362-585) antibody (Biotin)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 Biotin
anti-Versican (Vcan) (AA 362-585) antibody (PE)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 PE
anti-Versican (Vcan) (AA 362-585) antibody (APC)Vcan 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S351-23 APC
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应用备注
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WB 1:300-5000
IHC-P 1:200-400 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 12 months
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- Versican (Vcan)
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别名
- Versican
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背景
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Synonyms: Versican core protein, Chondroitin sulfate proteoglycan core protein 2, Glial hyaluronate-binding protein, Large fibroblast proteoglycan, PG-M, Chondroitin sulfate proteoglycan 2, GHAP, VCAN, CSPG2.
Background: Versican (chondroitin sulfate proteoglycan 2) is a large extracellular matrix proteoglycan involved in cell growth and differentiation. Important as a structural molecule, versican creates loose and hydrated matrices during key events in development and disease. The protein contains hyaluronic acid and glycosminoglycan-binding domains, epidermal growth factor-like repeats, a lectin-like sequence and a complement regulatory protein-like domain. Splice variants differ greatly in length and degree of modification by glycosaminoglycan chains. Accumulation around smooth muscle cells in lesions of atherosclerosis, suggests a role for versican in atherogenesis. Versican, differentially expressed in human melanoma, plays a role in tumor development and may be a reliable marker for clinical diagnosis. The organization of HA- and versican-rich pericellular matrices may facilitate migration and mitosis by diminishing cell surface adhesivity and affecting cell shape through steric exclusion and the viscous properties of HA proteoglycan gels. The human versican gene maps to chromosome 5q14.3.
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基因ID
- 1462
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UniProt
- P13611
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途径
- Glycosaminoglycan Metabolic Process
抗原
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