UBA1 抗体
Quick Overview for UBA1 抗体 (ABIN6945248)
抗原
See all UBA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Human Ubiquitin-like modifier-activating enzyme 1 between 1000 amino acids to C-terminus
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亚型
- IgG
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anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 300-600) antibody
UBA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) antibodyUBA1 适用: 人, 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 1-1058) antibodyUBA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 730-881) antibodyUBA1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) antibodyUBA1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 961-1058) antibodyUBA1 适用: 人, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (N-Term) antibodyUBA1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (N-Term) antibodyUBA1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (AA 800-850) antibodyUBA1 适用: 人 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1) (N-Term) antibodyUBA1 适用: 人, 大鼠, 小鼠, 犬, Cow, 马, 兔, 豚鼠, Bat, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))
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别名
- Ubiquitin-like modifier-activating enzyme 1
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背景
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Synonyms: Ubiquitin-like modifier-activating enzyme 1, Protein A1S9, Ubiquitin-activating enzyme E1, UBA1
Background: Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system (PubMed:1606621, PubMed:1447181). Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP (PubMed:1447181). Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (PubMed:22456334).
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基因ID
- 7317
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UniProt
- P22314
抗原
-
