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Transferrin Receptor 抗体

This anti-Transferrin Receptor antibody is a 兔 单克隆 antibody detecting Transferrin Receptor in FACS, WB, IHC, IHC (p) 和 IF (cc). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6945214
发货至: 中国

Quick Overview for Transferrin Receptor 抗体 (ABIN6945214)

抗原

See all Transferrin Receptor (TFRC) 抗体
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This Transferrin Receptor antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

8G6
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Human Transferrin Receptor between 100 to 450 amino acids

    亚型

    IgG
  • 应用备注

    WB 1:300-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()

    限制

    仅限研究用
  • 浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    别名

    Transferrin Receptor

    背景

    Synonyms: Transferrin receptor protein 1, T9, p90, CD_antigen: CD71, TR, TfR, TfR1, Trfr, TFRC

    Background: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

    UniProt

    P02786

    途径

    Transition Metal Ion Homeostasis
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