STING/TMEM173 抗体
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- 抗原 See all STING/TMEM173 (TMEM173) 抗体
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This STING/TMEM173 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within human TMEM173 aa 200 to the C-terminus
- 克隆位点
- 1B8
- 亚型
- IgG
- Top Product
- Discover our top product TMEM173 Primary Antibody
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- 应用备注
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WB 1:300-5000
FCM 1:20-100 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- 别名
- TMEM173 (TMEM173 产品)
- 别名
- ERIS antibody, MITA antibody, MPYS antibody, NET23 antibody, STING antibody, 2610307O08Rik antibody, Mita antibody, RGD1562552 antibody, transmembrane protein 173 antibody, TMEM173 antibody, Tmem173 antibody
- 背景
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Synonyms: Stimulator of interferon genes protein, Endoplasmic reticulum interferon stimulator, Mediator of IRF3 activation, Transmembrane protein 173, hSTING, ERIS, hMITA, TMEM173, ERIS, MITA, STING.
Background: Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
- 基因ID
- 340061
- UniProt
- Q86WV6
- 途径
- Activation of Innate immune Response
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