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TERT 抗体 (AA 1100-1200)

This 兔 单克隆 antibody specifically detects TERT in WB 和 FACS. It exhibits reactivity toward 人.
产品编号 ABIN6945141
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for TERT 抗体 (AA 1100-1200) (ABIN6945141)

抗原

See all TERT 抗体
TERT (Telomerase Reverse Transcriptase (TERT))

适用

  • 112
  • 10
  • 8
  • 5
  • 1
  • 1

宿主

  • 117
  • 7
  • 1

克隆类型

  • 99
  • 26
单克隆

标记

  • 55
  • 8
  • 8
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This TERT antibody is un-conjugated

应用范围

  • 75
  • 50
  • 42
  • 29
  • 25
  • 17
  • 16
  • 14
  • 10
  • 7
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Flow Cytometry (FACS)

克隆位点

1C1
  • 抗原表位

    • 16
    • 16
    • 10
    • 10
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1100-1200

    原理

    Telomerase reverse transcriptase (1C1) Monoclonal Antibody

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Human Telomerase reverse transcriptase between 1100 to 1200 amino acids

    亚型

    IgG
  • 应用备注

    WB(1:300-5000), FCM(1:20-100)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    TERT (Telomerase Reverse Transcriptase (TERT))

    别名

    Telomerase reverse transcriptase

    背景

    Synonyms: Telomerase reverse transcriptase, HEST2, Telomerase catalytic subunit, Telomerase-associated protein 2, TP2, TERT

    Background: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.

    基因ID

    7015

    UniProt

    O14746

    途径

    Telomere Maintenance
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