Recombinant tau 抗体 (pThr231)
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Quick Overview for Recombinant tau 抗体 (pThr231) (ABIN6945136)
抗原
See all tau 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr231
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原理
- phospho-Tau (Thr231) Recombinant Antibody
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic phospho-peptide surrounding Thr231 of human Tau
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亚型
- IgG
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应用备注
- WB(WB(1:500-2000))
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- tau (tau Protein)
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别名
- Tau
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背景
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Synonyms: Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT
Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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基因ID
- 4137
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UniProt
- P10636
抗原
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