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STIP1 抗体

This anti-STIP1 antibody is a 兔 单克隆 antibody detecting STIP1 in WB, FACS 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6945069
发货至: 中国

Quick Overview for STIP1 抗体 (ABIN6945069)

抗原

See all STIP1 抗体
STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

适用

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人, 小鼠, 大鼠

宿主

  • 65
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克隆类型

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单克隆

标记

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This STIP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

2H5
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant protein orresponding to human STIP1 aa 1-150

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

    别名

    STIP1

    背景

    Synonyms: Stress-induced-phosphoprotein 1, Hsc70/Hsp90-organizing protein, Renal carcinoma antigen NY-REN-11, Transformation-sensitive protein IEF SSP 3521, STI1, Hop, STIP1

    Background: Stress-induced-phosphoprotein 1 (STI1) functions as a co-chaperone for HSP70 and HSP90 during heat shock response. STI1 exists as either a monomer or a dimer, and this conformational flexibility facilitates its function in organizing HSP70/HSP90. HSP90 acts as an ATPase, and requires the recruitment of client proteins and proper conformation to function. STI1 acts as a "scaffold" for client protein recruitment to the relaxed, ADP-bound conformation of HSP90, thus suppressing ATP turnover during the loading phase and allowing proper function.

    基因ID

    10963

    UniProt

    P31948
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