SPCS2 抗体 (AA 2-100)
Quick Overview for SPCS2 抗体 (AA 2-100) (ABIN6945027)
抗原
See all SPCS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-100
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit,Zebrafish
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SPCS2
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亚型
- IgG
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anti-Signal Peptidase Complex Subunit 2 Homolog (SPCS2) (AA 7-86) antibody
SPCS2 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Peptidase Complex Subunit 2 Homolog (SPCS2) antibodySPCS2 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- SPCS2 (Signal Peptidase Complex Subunit 2 Homolog (SPCS2))
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别名
- SPCS2
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背景
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Synonyms: Microsomal signal peptidase 25 kDa subunit, Signal peptidase complex subunit 2, Signal peptidase complex subunit 2 homolog (S. cerevisiae), SPase 25 kDa subunit, SPCS2, SPCS2_HUMAN.
Background: SPCS2 is a 226 amino acid multi-pass membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER), and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS2 removes signal peptides from nascent proteins as they are translocated into the lumen of the ER. The gene encoding SPCS2 is located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
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基因ID
- 9789
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UniProt
- Q15005
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途径
- Peptide Hormone Metabolism
抗原
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