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SRSF3 抗体

This anti-SRSF3 antibody is a 兔 单克隆 antibody detecting SRSF3 in WB, IHC (p) 和 IF (cc). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6944869
发货至: 中国

Quick Overview for SRSF3 抗体 (ABIN6944869)

抗原

See all SRSF3 抗体
SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))

适用

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  • 6
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  • 2
  • 2
  • 1
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人, 小鼠, 大鼠

宿主

  • 30
  • 5

克隆类型

  • 29
  • 6
单克隆

标记

  • 29
  • 1
  • 1
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This SRSF3 antibody is un-conjugated

应用范围

  • 33
  • 19
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  • 9
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

9C11
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Full length recombinant protein.

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))

    别名

    SFRS3

    背景

    Synonyms: Serine/arginine-rich splicing factor 3, SRSF3, Pre-mRNA-splicing factor SRP20, Splicing factor arginine/serine-rich 3, SRP20

    Background: Splicing factor that specifically promotes exon-inclusion during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing. Also functions as export adapter involved in mRNA nuclear export. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway), enhances NXF1-NXT1 RNA-binding activity. Involved in nuclear export of m6A-containing mRNAs via interaction with YTHDC1: interaction with YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export. RNA-binding is semi-sequence specific

    基因ID

    6428

    UniProt

    P84103
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