SRSF1 抗体
Quick Overview for SRSF1 抗体 (ABIN6944863)
抗原
See all SRSF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within human SF2 aa 1-150
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亚型
- IgG
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anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (pSer1) antibody
SRSF1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (N-Term) antibodySRSF1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (AA 6-33), (N-Term) antibodySRSF1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (AA 158-186), (C-Term) antibodySRSF1 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20788 unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (C-Term) antibodySRSF1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 豚鼠, Cow, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (AA 16-224) antibodySRSF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (N-Term) antibodySRSF1 适用: 人, 小鼠, 大鼠 WB, IHC, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) antibodySRSF1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) (AA 11-38), (N-Term) antibodySRSF1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB22955 unconjugated
anti-serine/arginine-Rich Splicing Factor 1 (SRSF1) antibodySRSF1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 12 months
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- SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))
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别名
- SF2
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背景
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Synonyms: Serine/arginine-rich splicing factor 1, Alternative-splicing factor 1, Splicing factor, arginine/serine-rich 1, pre-mRNA-splicing factor SF2, P33 subunit, ASF-1, SRSF1, ASF, SF2, SF2P33, SFRS1, OK/SW-cl.3
Background: Pre-mRNA splicing enhancer elements are short RNA sequences capable of activating weak splice sites in nearby introns that are required for accurate splice site recognition and the control of alternative splicing. Splicing enhancer elements contain specific binding sites for serine/arginine (SR)-rich splicing factors, which include SC35, 9G8, SRp20, and SF2/ASF. The family of SR factors all contain one or more RNA recognition motifs (RRM) and an arginine/ serine (RS)-rich domain. They are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. The majority of SR proteins, including SC35 and SRp40, are confined to the nucleus, while SF2/ASF, SRp20, and 9G8 are continuously shuttled between the nucleus and the cytoplasm and contribute to mRNA transport. The activity of SR proteins in regulated splicing is antagonized by members of the hnRNP A/B family of proteins, which induce drastic shifts in the selection of splicing sites.
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UniProt
- Q07955
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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