SDCBP 抗体
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- 抗原 See all SDCBP 抗体
- SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This SDCBP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within human Syntenin aa 1-200.
- 克隆位点
- 2G6
- 亚型
- IgG
- Top Product
- Discover our top product SDCBP Primary Antibody
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- 应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg) - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))
- 别名
- SDCBP (SDCBP 产品)
- 别名
- MDA-9 antibody, ST1 antibody, SYCL antibody, TACIP18 antibody, Sycl antibody, syntenin-1 antibody, mda-9 antibody, st1 antibody, sycl antibody, tacip18 antibody, MGC81274 antibody, syntenin antibody, wu:fc51c03 antibody, wu:fk31e01 antibody, zgc:55679 antibody, zgc:77716 antibody, sb:eu862 antibody, si:dkey-235k4.1 antibody, syndecan binding protein antibody, syndecan binding protein L homeolog antibody, syndecan binding protein (syntenin) 2 antibody, syndecan binding protein (syntenin) antibody, SDCBP antibody, Sdcbp antibody, sdcbp.L antibody, LOC732879 antibody, sdcbp2 antibody, sdcbp antibody
- 背景
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Synonyms: Syntenin-1, Melanoma differentiation-associated protein 9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, Scaffold protein Pbp1, Syndecan-binding protein 1, MDA-9, TACIP18, SDCBP, MDA9, SYCL
Background: Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis. Positively regulates TGFB1-mediated SMAD2/3 activation and TGFB1-induced epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1. In concert with SDC1/4 and PDCD6IP, regulates exosome biogenesis. Regulates migration, growth, proliferation, and cell cycle progression in a variety of cancer type. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.
- 基因ID
- 6386
- UniProt
- O00560
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