SDCBP 抗体
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北京 101111
Quick Overview for SDCBP 抗体 (ABIN6944846)
抗原
See all SDCBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within human Syntenin aa 1-200.
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亚型
- IgG
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anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-100) antibody
SDCBP 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 2C12 unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-298) antibodySDCBP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) antibodyKD Validated SDCBP 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2185 unconjugated Recombinant Antibody
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 21-228) antibodySDCBP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-298) antibodySDCBP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-298) antibodyKD Validated SDCBP 适用: 人, 大鼠, 小鼠 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-260) antibodySDCBP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) antibodySDCBP 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (AA 1-30), (N-Term) antibodySDCBP 适用: 人 WB 宿主: 兔 Polyclonal RB42325 unconjugated
anti-Syndecan Binding Protein (Syntenin) (SDCBP) (Internal Region) antibodySDCBP 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg) -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))
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别名
- SDCBP
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背景
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Synonyms: Syntenin-1, Melanoma differentiation-associated protein 9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, Scaffold protein Pbp1, Syndecan-binding protein 1, MDA-9, TACIP18, SDCBP, MDA9, SYCL
Background: Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis. Positively regulates TGFB1-mediated SMAD2/3 activation and TGFB1-induced epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1. In concert with SDC1/4 and PDCD6IP, regulates exosome biogenesis. Regulates migration, growth, proliferation, and cell cycle progression in a variety of cancer type. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.
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基因ID
- 6386
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UniProt
- O00560
抗原
-
