Retinoid X Receptor alpha 抗体
Quick Overview for Retinoid X Receptor alpha 抗体 (ABIN6944804)
抗原
See all Retinoid X Receptor alpha (RXRA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein corresponding to N-terminal human Retinoid X Receptor alpha.
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亚型
- IgG
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anti-Retinoid X Receptor, alpha (RXRA) (AA 14-28) antibody
Verified RXRA 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Retinoid X Receptor, alpha (RXRA) antibodyRXRA 适用: 人 WB, IP, IF, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Retinoid X Receptor, alpha (RXRA) (N-Term) antibodyRXRA 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Retinoid X Receptor, alpha (RXRA) (AA 1-165) antibodyRXRA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3A5 unconjugated
anti-Retinoid X Receptor, alpha (RXRA) (AA 1-110) antibodyRXRA 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1G1 unconjugated
anti-Retinoid X Receptor, alpha (RXRA) (AA 1-462) antibodyRXRA 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Retinoid X Receptor, alpha (RXRA) (AA 1-165) antibodyRXRA 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4B5 unconjugated
anti-Retinoid X Receptor, alpha (RXRA) (AA 226-462) antibodyRXRA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Retinoid X Receptor, alpha (RXRA) (AA 196-224) antibodyRXRA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24547 unconjugated
anti-Retinoid X Receptor, alpha (RXRA) (AA 38-87) antibodyRXRA 适用: 人, 小鼠, 大鼠, 豚鼠, 犬, 马, 猴, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg) -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))
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别名
- RXRA
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背景
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Synonyms: Retinoic acid receptor RXR-alpha, Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha, RXRA, NR2B1
Background: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid. RXRA serves as a common heterodimeric partner for a number of nuclear receptors. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. The RXRA/PPARA heterodimer is required for PPARA transcriptional activity on fatty acid oxidation genes such as ACOX1 and the P450 system genes.
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基因ID
- 6256
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UniProt
- P19793
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途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C
抗原
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