RhoA,B,C 抗体
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北京 101111
Quick Overview for RhoA,B,C 抗体 (ABIN6944781)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant human RHOC protein
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亚型
- IgG
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anti-RhoA,B,C antibody
适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB850 unconjugated Recombinant Antibody
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- RhoA,B,C
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别名
- Rho A+B+C
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背景
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Synonyms: Transforming protein RhoA, Rho cDNA clone 12, Rho-related GTP-binding protein RhoB, Rho cDNA clone 6, Rho-related GTP-binding protein RhoC, Rho cDNA clone 9, h12, h6, h9, RHOA, RHOB, RHOC, RHOH12, RHOH6, RHOH9
Background: The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50 % amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7 and 8) are approximately 30 % homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy-terminal CAAX sequence (C, cysteine, A, aliphatic amino acid, X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.
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UniProt
- P08134, P61586, P62745
抗原
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