RAPGEF3 抗体 (AA 700-900)
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北京 101111
Quick Overview for RAPGEF3 抗体 (AA 700-900) (ABIN6944746)
抗原
See all RAPGEF3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 700-900
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原理
- RAPGEF3 (3D1) Monoclonal Antibody
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within human Epac1 aa 700-900
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亚型
- IgG
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anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 1-881) antibody
RAPGEF3 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 49-881) antibodyRAPGEF3 适用: 人, 小鼠, 猴 WB, ELISA, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 1-200) antibodyRAPGEF3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 772-881) antibodyRAPGEF3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 301-400) antibodyRAPGEF3 适用: 人 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) antibodyRAPGEF3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5060 unconjugated Recombinant Antibody
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (C-Term) antibodyRAPGEF3 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 359-408) antibodyRAPGEF3 适用: 人, 小鼠, 大鼠, 猴, 马, Cow, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 107-156) antibodyRAPGEF3 适用: 人, 小鼠, 大鼠, 猴, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3) (AA 772-881) antibodyRAPGEF3 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB(1:300-5000), IHC-P(1:200-400)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 12 months
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- RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))
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别名
- RAPGEF3
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背景
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Synonyms: Rap guanine nucleotide exchange factor 3, Exchange factor directly activated by cAMP 1, Exchange protein directly activated by cAMP 1, Rap1 guanine-nucleotide-exchange factor directly activated by cAMP, cAMP-regulated guanine nucleotide exchange factor I, EPAC 1, cAMP-GEFI, RAPGEF3, CGEF1, EPAC, EPAC1, bcm910, HSU79275.
Background: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin.
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基因ID
- 10411
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UniProt
- O95398
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途径
- cAMP Metabolic Process
抗原
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