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Progesterone Receptor 抗体 (AA 221-320) (FITC)

PGR 适用: 人, 大鼠, 小鼠, 绵羊 WB, IF (p), IF (cc) 宿主: 兔 Polyclonal FITC
产品编号 ABIN6944677
发货至: 中国
  • 抗原 See all Progesterone Receptor (PGR) 抗体
    Progesterone Receptor (PGR)
    抗原表位
    • 16
    • 16
    • 14
    • 11
    • 10
    • 10
    • 9
    • 8
    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
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    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 221-320
    适用
    • 208
    • 38
    • 35
    • 15
    • 15
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠, 绵羊
    宿主
    • 148
    • 64
    • 1
    克隆类型
    • 141
    • 71
    • 1
    多克隆
    标记
    • 128
    • 15
    • 9
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Progesterone Receptor antibody is conjugated to FITC
    应用范围
    • 174
    • 84
    • 60
    • 32
    • 30
    • 25
    • 25
    • 24
    • 19
    • 18
    • 17
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 小鼠, 大鼠, 绵羊
    预测反应
    Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Progesterone Receptor
    亚型
    IgG
    Top Product
    Discover our top product PGR Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Progesterone Receptor (PGR)
    别名
    Progesterone Receptor (PGR 产品)
    背景

    Synonyms: NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, Progesterone receptor, Progestin receptor form A, Progestin receptor form B, PRGR_HUMAN, Progestin receptor form A, Progestin receptor form B.

    Background: Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands. The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes. The carboxy terminal region of the estrgen receptor contains the ligand binding domain, the amino terminus serves as the transactivation domain, and the DNA binding domain is centrally located. Two forms of estrogen receptor have been identified, ER alpha and ER beta. ER alpha and ER beta have been shown to be differentially activated by various ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-Aand hPR-B), which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors.

    基因ID
    5241
    UniProt
    P06401
    途径
    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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