Pro Caspase 9 抗体
适用: 人
FACS, WB
宿主: 兔
Monoclonal
3T6
unconjugated
-
- 抗原
- Pro Caspase 9
- 适用
- 人
-
宿主
- 兔
-
克隆类型
- 单克隆
-
标记
- 非结合性
- 应用范围
- Flow Cytometry (FACS), Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- Human Caspase-9 between 250 to 350 amino acids
- 克隆位点
- 3T6
- 亚型
- IgG
-
-
- 应用备注
-
WB 1:300-5000
FCM 1:20-100 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
-
- 抗原
- Pro Caspase 9
- 背景
-
Synonyms: Caspase-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP-9, APAF-3, ICE-LAP6, CASP9
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
- 基因ID
- 842
- UniProt
- P55211
-
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