Pro Caspase 3 抗体
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北京 101111
Quick Overview for Pro Caspase 3 抗体 (ABIN6944660)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- pro Caspase 3 (12B1) Monoclonal Antibody
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by Protein A.
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亚型
- IgG
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anti-Pro Caspase 3 antibody
KD Validated 适用: 人 FACS, WB, IF (p) 宿主: 兔 Monoclonal 23GB715 unconjugated Recombinant Antibody
anti-Pro Caspase 3 antibodyKD Validated 适用: 人 FACS, WB, IF (p) 宿主: 兔 Monoclonal 23GB710 unconjugated Recombinant Antibody
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应用备注
- WB(1:300-5000), FCM(1:50-200), IHC-P(1:200-400), IF(ICC)(1:50-200)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- Pro Caspase 3
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背景
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Synonyms: Caspase-3, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, CASP-3, CPP-32, SCA-1, CASP3
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
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基因ID
- 836
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UniProt
- P42574
抗原
-
