Pro Caspase 3 抗体
Our Local Distributor
北京 101111
Quick Overview for Pro Caspase 3 抗体 (ABIN6944660)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应
- 人, 小鼠
-
纯化方法
- Purified by Protein A.
-
亚型
- IgG
-
-
anti-Pro Caspase 3 antibody
KD Validated 适用: 人 FACS, WB, IF (p) 宿主: 兔 Monoclonal 23GB715 unconjugated Recombinant Antibody
anti-Pro Caspase 3 antibodyKD Validated 适用: 人 FACS, WB, IF (p) 宿主: 兔 Monoclonal 23GB710 unconjugated Recombinant Antibody
-
-
应用备注
-
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C for 12 months.
-
有效期
- 12 months
-
-
- Pro Caspase 3
-
背景
-
Synonyms: Caspase-3, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, CASP-3, CPP-32, SCA-1, CASP3
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
-
基因ID
- 836
-
UniProt
- P42574
抗原
-
