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PKC mu 抗体

PRKD1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Monoclonal 10C1 unconjugated
产品编号 ABIN6944657
发货至: 中国
  • 抗原 See all PKC mu (PRKD1) 抗体
    PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))
    适用
    • 128
    • 84
    • 72
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    人, 小鼠, 大鼠
    宿主
    • 141
    • 2
    • 2
    克隆类型
    • 136
    • 9
    单克隆
    标记
    • 67
    • 9
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    This PKC mu antibody is un-conjugated
    应用范围
    • 96
    • 47
    • 40
    • 40
    • 29
    • 17
    • 15
    • 10
    • 6
    • 6
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Human PKC mu aa 500-650
    克隆位点
    10C1
    亚型
    IgG
    Top Product
    Discover our top product PRKD1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))
    别名
    PRKD1 (PRKD1 产品)
    别名
    MGC83727 antibody, PRKD1 antibody, pkd antibody, pkcm antibody, prkcm antibody, pkc-mu antibody, PKC-MU antibody, PKCM antibody, PKD antibody, PRKCM antibody, PKD1 antibody, Pkcm antibody, Prkcm antibody, nPKC-D1 antibody, nPKC-mu antibody, PKC antibody, protein kinase D1 antibody, protein kinase D1 L homeolog antibody, PRKD1 antibody, prkd1.L antibody, prkd1 antibody, Prkd1 antibody
    背景

    Synonyms: Serine/threonine-protein kinase D1, Protein kinase C mu type, Protein kinase D, nPKC-D1, nPKC-mu, PRKD1, PKD, PKD1, PRKCM, PKC mu, CHDED.

    Background: Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. In epithelial cells, is required for transducing flagellin-stimulated inflammatory responses by binding and phosphorylating TLR5, which contributes to MAPK14/p38 activation and production of inflammatory cytokines. May play a role in inflammatory response by mediating activation of NF-kappa-B. May be involved in pain transmission by directly modulating TRPV1 receptor. Plays a role in activated KRAS-mediated stabilization of ZNF304 in colorectal cancer (CRC) cells. Regulates nuclear translocation of transcription factor TFEB in macrophages upon live S.enterica infection.

    基因ID
    5587
    UniProt
    Q15139
    途径
    Myometrial Relaxation and Contraction
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