PKC mu 抗体
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- 抗原 See all PKC mu (PRKD1) 抗体
- PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This PKC mu antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Human PKC mu aa 500-650
- 克隆位点
- 10C1
- 亚型
- IgG
- Top Product
- Discover our top product PRKD1 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))
- 别名
- PRKD1 (PRKD1 产品)
- 别名
- MGC83727 antibody, PRKD1 antibody, pkd antibody, pkcm antibody, prkcm antibody, pkc-mu antibody, PKC-MU antibody, PKCM antibody, PKD antibody, PRKCM antibody, PKD1 antibody, Pkcm antibody, Prkcm antibody, nPKC-D1 antibody, nPKC-mu antibody, PKC antibody, protein kinase D1 antibody, protein kinase D1 L homeolog antibody, PRKD1 antibody, prkd1.L antibody, prkd1 antibody, Prkd1 antibody
- 背景
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Synonyms: Serine/threonine-protein kinase D1, Protein kinase C mu type, Protein kinase D, nPKC-D1, nPKC-mu, PRKD1, PKD, PKD1, PRKCM, PKC mu, CHDED.
Background: Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. In epithelial cells, is required for transducing flagellin-stimulated inflammatory responses by binding and phosphorylating TLR5, which contributes to MAPK14/p38 activation and production of inflammatory cytokines. May play a role in inflammatory response by mediating activation of NF-kappa-B. May be involved in pain transmission by directly modulating TRPV1 receptor. Plays a role in activated KRAS-mediated stabilization of ZNF304 in colorectal cancer (CRC) cells. Regulates nuclear translocation of transcription factor TFEB in macrophages upon live S.enterica infection.
- 基因ID
- 5587
- UniProt
- Q15139
- 途径
- Myometrial Relaxation and Contraction
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