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PKC mu 抗体

The 兔 单克隆 anti-PKC mu antibody (Clone 10C1) (ABIN6944657) specifically detects PKC mu in WB 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6944657
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for PKC mu 抗体 (ABIN6944657)

抗原

See all PKC mu (PRKD1) 抗体
PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

适用

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人, 小鼠, 大鼠

宿主

  • 137
  • 2
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克隆类型

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  • 10
单克隆

标记

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This PKC mu antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

10C1
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Human PKC mu aa 500-650

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PKC mu (PRKD1) (Protein Kinase D1 (PRKD1))

    别名

    PRKD1

    背景

    Synonyms: Serine/threonine-protein kinase D1, Protein kinase C mu type, Protein kinase D, nPKC-D1, nPKC-mu, PRKD1, PKD, PKD1, PRKCM, PKC mu, CHDED.

    Background: Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. In epithelial cells, is required for transducing flagellin-stimulated inflammatory responses by binding and phosphorylating TLR5, which contributes to MAPK14/p38 activation and production of inflammatory cytokines. May play a role in inflammatory response by mediating activation of NF-kappa-B. May be involved in pain transmission by directly modulating TRPV1 receptor. Plays a role in activated KRAS-mediated stabilization of ZNF304 in colorectal cancer (CRC) cells. Regulates nuclear translocation of transcription factor TFEB in macrophages upon live S.enterica infection.

    基因ID

    5587

    UniProt

    Q15139

    途径

    Myometrial Relaxation and Contraction
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