Neuropilin 1 抗体
-
- 抗原 See all Neuropilin 1 (NRP1) 抗体
- Neuropilin 1 (NRP1)
-
适用
- 人, 大鼠, 小鼠
-
宿主
- 兔
-
克隆类型
- 单克隆
-
标记
- This Neuropilin 1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Human Neuropilin 1 between 900 to C-terminus
- 克隆位点
- 49H9
- 亚型
- IgG
- Top Product
- Discover our top product NRP1 Primary Antibody
-
-
- 应用备注
-
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- Neuropilin 1 (NRP1)
- 别名
- Neuropilin-1 (NRP1 产品)
- 别名
- NRP1 antibody, cd304 antibody, neuropilin antibody, np-1 antibody, npn-1 antibody, nrp antibody, nrp-1 antibody, vegf165r antibody, BDCA4 antibody, CD304 antibody, NP1 antibody, NRP antibody, VEGF165R antibody, C530029I03 antibody, NP-1 antibody, NPN-1 antibody, Npn1 antibody, Nrp antibody, neuropilin 1 antibody, neuropilin 1 L homeolog antibody, NRP1 antibody, nrp1 antibody, Nrp1 antibody, nrp1.L antibody
- 背景
-
Synonyms: Neuropilin-1, Vascular endothelial cell growth factor 165 receptor, CD_antigen: CD304, NRP1, NRP, VEGF165R
Background: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.
- 基因ID
- 8829
- UniProt
- O14786
- 途径
- Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals
-