NDUFA13 抗体 (AA 1-150)
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北京 101111
Quick Overview for NDUFA13 抗体 (AA 1-150) (ABIN6944230)
抗原
See all NDUFA13 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-150
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原理
- NDUFA13 (4F12) Monoclonal Antibody
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within human GRIM19 aa 1-150.
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亚型
- IgG
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应用备注
- WB(1:300-5000), IHC-P(1:50-200), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- NDUFA13 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 13 (NDUFA13))
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别名
- NDUFA13
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背景
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Synonyms: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, Cell death regulatory protein GRIM-19, Complex I-B16.6, Gene associated with retinoic and interferon-induced mortality 19 protein, NADH-ubiquinone oxidoreductase B16.6 subunit, CI-B16.6, GRIM-19, Gene associated with retinoic and IFN-induced mortality 19 protein, NDUFA13, GRIM19
Background: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes
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基因ID
- 51079
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UniProt
- Q9P0J0
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途径
- Protein targeting to Nucleus, Negative Regulation of intrinsic apoptotic Signaling
抗原
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