NCK1 抗体
Quick Overview for NCK1 抗体 (ABIN6944225)
抗原
See all NCK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by Protein A.
-
免疫原
- Recombinant protein corresponding human Nck1 aa 1-200
-
亚型
- IgG
-
-
anti-NCK Adaptor Protein 1 (NCK1) antibody
NCK1 适用: 人, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 185-294) antibodyNCK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-NCK Adaptor Protein 1 (NCK1) antibodyNCK1 适用: 人, 猴 WB, FACS, IHC (p), EIA 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 58-377) antibodyNCK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) antibodyNCK1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 1-377) antibodyNCK1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 53-333) antibodyNCK1 适用: 人 WB, IHC, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (AA 1-377) antibodyNCK1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) (Internal Region) antibodyNCK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-NCK Adaptor Protein 1 (NCK1) antibodyNCK1 适用: 人, 小鼠 WB, ICC 宿主: 小鼠 Monoclonal EM-06 unconjugated
-
-
应用备注
-
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
有效期
- 12 months
-
-
- NCK1 (NCK Adaptor Protein 1 (NCK1))
-
别名
- NCK1
-
背景
-
Synonyms: Cytoplasmic protein NCK1, NCK adaptor protein 1, SH2/SH3 adaptor protein NCK-alpha, Nck-1, NCK1, NCK.
Background: Adapter protein which associates with tyrosine-phosphorylated growth factor receptors, such as KDR and PDGFRB, or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in the DNA damage response, not in the detection of the damage by ATM/ATR, but for efficient activation of downstream effectors, such as that of CHEK2. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling. Modulates the activation of EIF2AK2/PKR by dsRNA. May play a role in cell adhesion and migration through interaction with ephrin receptors.
-
基因ID
- 4690
-
UniProt
- P16333
-
途径
- TCR Signaling, Regulation of Actin Filament Polymerization, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
-
