Recombinant MMP13 抗体
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北京 101111
Quick Overview for Recombinant MMP13 抗体 (ABIN6944105)
抗原
See all MMP13 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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原理
- MMP13 Recombinant Antibody
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交叉反应
- 人
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预测反应
- Mouse
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纯化方法
- Purified by Protein A.
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免疫原
- N terminus human MMP13
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亚型
- IgG
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应用备注
- WB(WB(1:500-2000))
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
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别名
- MMP13
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背景
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Synonyms: Collagenase 3, Matrix metalloproteinase-13, MMP-13, MMP13
Background: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
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基因ID
- 4322
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UniProt
- P45452
抗原
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