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Recombinant MLKL 抗体 (C-Term)

This 兔 单克隆 antibody specifically detects MLKL in WB. It exhibits reactivity toward 人.
产品编号 ABIN6944094
发货至: 中国
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Quick Overview for Recombinant MLKL 抗体 (C-Term) (ABIN6944094)

抗原

See all MLKL 抗体
MLKL (Mixed Lineage Kinase Domain-Like (MLKL))

抗体类型

Recombinant Antibody

适用

  • 87
  • 65
  • 25
  • 1
  • 1

宿主

  • 113
  • 10

克隆类型

  • 63
  • 60
单克隆

标记

  • 46
  • 10
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 5
  • 5
  • 5
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
This MLKL antibody is un-conjugated

应用范围

  • 85
  • 52
  • 32
  • 28
  • 18
  • 17
  • 13
  • 7
  • 1
Western Blotting (WB)
  • 抗原表位

    • 22
    • 13
    • 12
    • 9
    • 7
    • 7
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    MLKL Recombinant Antibody

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Human MLKL between 350 to C-terminus

    亚型

    IgG
  • 应用备注

    WB(WB(1:500-2000))

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    MLKL (Mixed Lineage Kinase Domain-Like (MLKL))

    别名

    MLKL

    背景

    Synonyms: Mixed lineage kinase domain-like protein, hMLKL, MLKL

    Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity (PubMed:22265413, PubMed:22265414, PubMed:22421439, PubMed:24316671). Binds to highly phosphorylated inositol phosphates such as inositolhexakisphosphate (InsP6) which is essential for its necroptotic function (PubMed:29883610).

    基因ID

    197259

    UniProt

    Q8NB16
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