Recombinant MLKL 抗体 (pSer345)
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北京 101111
Quick Overview for Recombinant MLKL 抗体 (pSer345) (ABIN6944093)
抗原
See all MLKL 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer345
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原理
- phospho-MLKL (Ser345) Recombinant Antibody
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交叉反应
- 小鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL
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亚型
- IgG
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应用备注
- WB(1:500-2000), ICC/IF(1:50-200)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
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别名
- MLKL
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背景
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Synonyms: Phospho-MLKL (S345), pMLKL Ser345, Mixed lineage kinase domain-like protein, Mlkl
Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
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基因ID
- 74568
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UniProt
- Q9D2Y4
抗原
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