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MLKL 抗体 (pSer345)

This anti-MLKL antibody is a 兔 单克隆 antibody detecting MLKL in WB, IHC (p) 和 IF (cc). Suitable for 小鼠.
产品编号 ABIN6944093
发货至: 中国

Quick Overview for MLKL 抗体 (pSer345) (ABIN6944093)

抗原

See all MLKL 抗体
MLKL (Mixed Lineage Kinase Domain-Like (MLKL))

适用

  • 49
  • 40
  • 20
  • 1
  • 1
  • 1
小鼠

宿主

  • 61
  • 6

克隆类型

  • 46
  • 21
单克隆

标记

  • 41
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This MLKL antibody is un-conjugated

应用范围

  • 37
  • 30
  • 19
  • 12
  • 6
  • 5
  • 5
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

7G4
  • 抗原表位

    • 10
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    • 2
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    • 1
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    pSer345

    交叉反应

    小鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    MLKL (Mixed Lineage Kinase Domain-Like (MLKL))

    别名

    MLKL

    背景

    Synonyms: Phospho-MLKL (S345), pMLKL Ser345, Mixed lineage kinase domain-like protein, Mlkl

    Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

    基因ID

    74568

    UniProt

    Q9D2Y4
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