MLKL 抗体 (pSer345)
Quick Overview for MLKL 抗体 (pSer345) (ABIN6944093)
抗原
See all MLKL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer345
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交叉反应
- 小鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
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别名
- MLKL
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背景
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Synonyms: Phospho-MLKL (S345), pMLKL Ser345, Mixed lineage kinase domain-like protein, Mlkl
Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
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基因ID
- 74568
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UniProt
- Q9D2Y4
抗原
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