MARK3 抗体 (AA 600-750)
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北京 101111
Quick Overview for MARK3 抗体 (AA 600-750) (ABIN6944028)
抗原
See all MARK3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 600-750
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原理
- MARK3 Recombinant Antibody
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交叉反应
- 人
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预测反应
- Mouse
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within human Mark3 aa 600-750.
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亚型
- IgG
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应用备注
- WB(1:500-2000), FCM(1:50-100)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- MARK3 (MAP/microtubule Affinity-Regulating Kinase 3 (MARK3))
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别名
- MARK3
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背景
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Synonyms: MAP/microtubule affinity-regulating kinase 3, C-TAK1, cTAK1, Cdc25C-associated protein kinase 1, ELKL motif kinase 2, EMK-2, Protein kinase STK10, Ser/Thr protein kinase PAR-1, Par-1a, Serine/threonine-protein kinase p78, microtubule affinity regulating kinase 3
Background: Serine/threonine-protein kinase. Involved in the specific phosphorylation of microtubule-associated proteins for MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus. Negatively regulates the Hippo signaling pathway and antagonizes the phosphorylation of LATS1. Cooperates with DLG5 to inhibit the kinase activity of STK3/MST2 toward LATS1.
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基因ID
- 4140
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UniProt
- P27448
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途径
- SARS-CoV-2 Protein Interactome
抗原
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