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MYST1 抗体

KAT8 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), IHC (p), FACS 宿主: 兔 Monoclonal 2B1 unconjugated
产品编号 ABIN6943861
发货至: 中国
  • 抗原 See all MYST1 (KAT8) 抗体
    MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))
    适用
    • 55
    • 47
    • 28
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 64
    • 6
    克隆类型
    • 57
    • 13
    单克隆
    标记
    • 31
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This MYST1 antibody is un-conjugated
    应用范围
    • 54
    • 26
    • 26
    • 20
    • 12
    • 7
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant protein within N-terminal human KAT8.
    克隆位点
    2B1
    亚型
    IgG
    Top Product
    Discover our top product KAT8 Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    MYST1 (KAT8) (K(lysine) Acetyltransferase 8 (KAT8))
    别名
    KAT8 (KAT8 产品)
    别名
    myst1 antibody, wu:fb22g02 antibody, wu:fj22d09 antibody, zgc:66387 antibody, Myst1 antibody, MOF antibody, MYST1 antibody, ZC2HC8 antibody, hMOF antibody, 2010203C02Rik antibody, 5830450F21Rik antibody, D7Ertd629e antibody, K(lysine) acetyltransferase 8 antibody, lysine acetyltransferase 8 antibody, kat8 antibody, KAT8 antibody, Kat8 antibody
    背景

    Synonyms: Histone acetyltransferase KAT8, Lysine acetyltransferase 8, MOZ YBF2/SAS3 SAS2 and TIP60 protein 1, MYST-1, hMOF, KAT8, MOF, MYST1

    Background: Dosage compensation ensures that males with a single X chromosome and females with two X chromosomes have the same amount of most X-linked gene products. In Drosophila, this is acheived by enhancing the level of transcription of the X chromosome in males. Proteins such as maleless, male specific lethal 1, 2 and 3, and males absent on the first (MOF) form a dosage compensation complex (DCC) that is required for the twofold increase of transcription of the male X chromosome. The DCC is preferentially associated with many sites on the X chromosome in somatic cells of males. The binding of the DCC to the X chromosome is dependent upon histone 4 acetylation at lysine 16, which is accomplished by MOF. In mammals, MOF (also designated hMOF, MYST1, or MOZ) belongs to the MYST family of histone acetyl transferases which are characterized by a unique C2HC-type zinc finger close to their HAT domains. MOF utilizes the zinc finger domain to contact the globular part of the nucleosome as well as the histone H4 N-terminal tail substrate. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone acetyltransferases.

    基因ID
    84148
    UniProt
    Q9H7Z6
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