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KARS 抗体

The 兔 单克隆 anti-KARS antibody is suitable to detect KARS in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IP 和 IHC (p).
产品编号 ABIN6943858
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KARS 抗体 (ABIN6943858)

抗原

See all KARS 抗体
KARS (Lysyl-tRNA Synthetase (KARS))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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单克隆

标记

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This KARS antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

1H8
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant protein corresponding to C-terminal human Lysyl tRNA synthetase.

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IP(1-2 μg)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    KARS (Lysyl-tRNA Synthetase (KARS))

    别名

    KARS

    背景

    Synonyms: Lysine tRNA ligase, Lysyl tRNA synthetase, LysRS, KARS, KIAA0070

    Background: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity.

    基因ID

    3735

    UniProt

    Q15046
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