KARS 抗体 (C-Term)
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北京 101111
Quick Overview for KARS 抗体 (C-Term) (ABIN6943858)
抗原
See all KARS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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原理
- Lysyl-tRNA synthetase (1H8) Monoclonal Antibody
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein corresponding to C-terminal human Lysyl tRNA synthetase.
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亚型
- IgG
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应用备注
- WB(1:300-5000), IHC-P(1:200-400), IP(1-2 μg)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- KARS (Lysyl-tRNA Synthetase (KARS))
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别名
- KARS
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背景
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Synonyms: Lysine tRNA ligase, Lysyl tRNA synthetase, LysRS, KARS, KIAA0070
Background: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity.
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基因ID
- 3735
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UniProt
- Q15046
抗原
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