JNK1/JNK2/JNK3 抗体
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- 抗原 See all JNK1/JNK2/JNK3 products
- JNK1/JNK2/JNK3
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适用
- 小鼠, 大鼠, 人, 猴, 斑马鱼
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This JNK1/JNK2/JNK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人, 猴, 小鼠, 大鼠, 斑马鱼
- 纯化方法
- Purified by Protein A.
- 免疫原
- Human JNK1+JNK2+JNK3 between 1 to 400 amino acids
- 克隆位点
- 3G7
- 亚型
- IgG
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anti-JNK1/JNK2/JNK3 (pThr183), (pThr221) antibody
适用: 小鼠, 大鼠, 人 WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- JNK1/JNK2/JNK3
- 别名
- JNK1+JNK2+JNK3 (JNK1/JNK2/JNK3 产品)
- 背景
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Synonyms: C Jun kinase 2, c Jun N terminal kinase 1, c Jun N terminal kinase 2, c Jun N terminal kinase 3, c-Jun N-terminal kinase 1, JNK 46, JNK 55, JNK, JNK-46, JNK1, JNK1A2, JNK2, JNK21B1/2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, JNK3 alpha protein kinase, JNK3, JNK3A, Jun kinase, JUN N terminal kinase, MAP kinase 10, MAP kinase 8, MAP kinase 9, MAP kinase p49 3F12, MAPK 10, MAPK 8, MAPK 9, MAPK10, mapk8, MAPK9, Mitogen activated protein kinase 10, Mitogen activated protein kinase 8, Mitogen activated protein kinase 8 isoformJNK1 alpha1, Mitogen activated protein kinase 8 isoform JNK1 beta2, Mitogen activated protein kinase 9, Mitogen-activated protein kinase 8, MK08_HUMAN, p493F12, p54a, p54aSAPK, p54bSAPK, PRKM10, PRKM8, PRKM9, SAPK, SAPK(beta), SAPK1, SAPK1a, SAPK1b, SAPK1c, Stress activated protein kinase 1, Stress activated protein kinase1a, Stress activated protein kinase 1b, Stress activated protein kinase 1c, Stress activated protein kinase beta, Stress activated protein kinase JNK1, Stressactivated protein kinase JNK2, Stress activated protein kinase JNK3, Stressactivated protein kinase 1c, Stress-activated protein kinase JNK1,
Background: c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield 10 isoforms through alternative mRNA splicing, including JNK1a1,JNK1b1, JNK2a1, JNK2b1, and JNK3a1, which represent the p46 isoforms, and JNK1a2, JNK1b2, JNK2a2, JNK2b2, and JNK3b2, which represent the p54 isoforms.JNKs coordinate cell responses to stress and influence regulation of cell growth and transformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83 % amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun, and other signaling kinases, including MEKK1 and p38.
- UniProt
- P45983, P45984, P53779
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