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Integrin beta 4 抗体

This anti-Integrin beta 4 antibody is a 兔 单克隆 antibody detecting Integrin beta 4 in WB, IHC 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN6943811
发货至: 中国

Quick Overview for Integrin beta 4 抗体 (ABIN6943811)

抗原

See all Integrin beta 4 (ITGB4) 抗体
Integrin beta 4 (ITGB4)

适用

  • 91
  • 26
  • 24
  • 4
  • 4
人, 小鼠

宿主

  • 64
  • 38
  • 10
  • 2

克隆类型

  • 58
  • 56
单克隆

标记

  • 64
  • 9
  • 7
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Integrin beta 4 antibody is un-conjugated

应用范围

  • 58
  • 50
  • 42
  • 34
  • 23
  • 22
  • 16
  • 13
  • 13
  • 13
  • 9
  • 8
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

6C1
  • 交叉反应

    人, 小鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Human Integrin beta 4 between 1750-1850 amino acids

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Integrin beta 4 (ITGB4)

    别名

    Integrin beta 4

    背景

    Synonyms: Integrin beta-4, GP150, CD104, ITGB4

    Background: Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464).

    UniProt

    P16144

    途径

    Integrin Complex
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