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HNRNPC 抗体

HNRNPC 适用: 人, 大鼠, 小鼠, 斑马鱼 WB, IHC, IHC (p), IF (cc), FACS 宿主: 兔 Monoclonal 9F7 unconjugated
产品编号 ABIN6943686
发货至: 中国
  • 抗原 See all HNRNPC 抗体
    HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
    适用
    • 57
    • 48
    • 33
    • 8
    • 7
    • 6
    • 6
    • 6
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    • 2
    • 2
    • 1
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    • 1
    人, 大鼠, 小鼠, 斑马鱼
    宿主
    • 70
    • 2
    克隆类型
    • 62
    • 10
    单克隆
    标记
    • 38
    • 4
    • 2
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    • 2
    • 2
    • 2
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    • 2
    • 2
    • 1
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    • 1
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    • 1
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    This HNRNPC antibody is un-conjugated
    应用范围
    • 42
    • 26
    • 25
    • 15
    • 15
    • 13
    • 13
    • 7
    • 3
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    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)
    交叉反应
    人, 小鼠, 大鼠, 斑马鱼
    纯化方法
    Purified by Protein A.
    免疫原
    Full length protein
    克隆位点
    9F7
    亚型
    IgG
    Top Product
    Discover our top product HNRNPC Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
    别名
    hnRNP C1+C2 (HNRNPC 产品)
    背景

    Synonyms: Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2, HNRNPC

    Background: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621). Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides (PubMed:8264621). May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm6A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671).

    基因ID
    3183
    UniProt
    P07910
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