GRIA2 抗体
Quick Overview for GRIA2 抗体 (ABIN6943574)
抗原
See all GRIA2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within Human GluR2 aa 50-250
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亚型
- IgG
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anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 652-807) antibody
GRIA2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7G6 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 35-175) antibodyGRIA2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7A7A3 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 25-360) antibodyGRIA2 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 413-527) antibodyGRIA2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 175-430) antibodyGRIA2 适用: 人, 大鼠, 小鼠, 猴 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 25-360) antibodyGRIA2 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, FACS, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (N-Term) antibodyGRIA2 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (C-Term) antibodyGRIA2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (C-Term) antibodyGRIA2 适用: 大鼠 WB, IHC, IP, FM 宿主: 小鼠 Monoclonal S21-32 unconjugated
anti-Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (AA 151-250) antibodyGRIA2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (p), IF (cc), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 12 months
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- GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
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别名
- GRIA2
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背景
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Synonyms: GLUR2, Glutamate receptor 2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic AMPA 2, GluR-2, GluA2, GRIA2, GLURB, HBGR2.
Background: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. Through complex formation with NSG1, GRIP1 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting
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基因ID
- 2891
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UniProt
- P42262
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途径
- PI3K-Akt Signaling
抗原
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