GOPC 抗体 (AA 1-100)
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北京 101111
Quick Overview for GOPC 抗体 (AA 1-100) (ABIN6943566)
抗原
See all GOPC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-100
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原理
- GOPC (1B8) Monoclonal Antibody
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant protein within human PIST aa 1-100.
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亚型
- IgG
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应用备注
- WB(1:500-2000), FCM(1:100-500), IHC-P(1:400-800), IF(IHC-P)(1:100-500), IF(ICC)(1:50-100), IP(1-2 μg)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- GOPC (Golgi-Associated PDZ and Coiled-Coil Motif Containing (GOPC))
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别名
- GOPC
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背景
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Synonyms: Golgi-associated PDZ and coiled-coil motif-containing protein, CFTR-associated ligand, Fused in glioblastoma, PDZ protein interacting specifically with TC10, PIST, GOPC
Background: Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.
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基因ID
- 57120
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UniProt
- Q9HD26
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途径
- Maintenance of Protein Location, Asymmetric Protein Localization
抗原
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