Glycogen Synthase 抗体 (AA 700-800)
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Quick Overview for Glycogen Synthase 抗体 (AA 700-800) (ABIN6943562)
抗原
See all Glycogen Synthase (GYS) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 700-800
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原理
- Glycogen synthase (1A8) Monoclonal Antibody
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Recombinant human Glycogen synthase between 700 to 800 amino acids
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亚型
- IgG
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应用备注
- WB(1:300-5000), FCM(1:20-100)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- Glycogen Synthase (GYS)
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别名
- Glycogen synthase
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背景
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Synonyms: Glycogen [starch] synthase, muscle, GYS1
Background: Glycogen Synthase (GS) is a key enzyme in the regulation of glycogen metabolism. GS catalyzes the incorporation of UDP-glucose incorporation into glycogen. The activity of glycogen synthase is regulated by hormonal stimuli (insulin, catecholamines and glucagons) and non-hormonal stimuli (blood glucose level and exercise). Two main isoforms of mammalian GS are designated as muscle (glycogen synthase 1) and liver (glycogen synthase 2). Most tissues express glycogen synthase 1, whereas glycogen synthase 2 appears to be tissue-specific. The two isoforms have 70 % identical amino acid sequence. Glycogen synthase can be phosphorylated by multiple kinases including glycogen synthase kinase-3 (GSK-3), mitogen-activated protein kinase-related protein kinase (DYRK), and SAPK2b/p38b which leads to its inactivation.
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基因ID
- 2997
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UniProt
- P13807
抗原
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