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Frataxin 抗体

The 兔 单克隆 anti-Frataxin antibody (Clone 2G1) (ABIN6943478) specifically detects Frataxin in WB. The antibody is reactive with 人 samples.
产品编号 ABIN6943478
发货至: 中国
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Quick Overview for Frataxin 抗体 (ABIN6943478)

抗原

See all Frataxin (FXN) 抗体
Frataxin (FXN)

适用

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宿主

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克隆类型

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单克隆

标记

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This Frataxin antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

2G1
  • 交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Full length recombinant human Frataxin protein

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Frataxin (FXN)

    别名

    FRATAXIN

    背景

    Synonyms: Frataxin, mitochondrial, FXN, Friedreich ataxia protein, FRDA, X25

    Background: Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe2+ to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress through its ability to catalyze the oxidation of Fe2+ to Fe3+, the oligomeric form but not the monomeric form has in vitro ferroxidase activity. May be able to store large amounts of iron in the form of a ferrihydrite mineral by oligomerization, however, the physiological relevance is unsure as reports are conflicting and the function has only been shown using heterologous overexpression systems. Modulates the RNA-binding activity of ACO1.

    基因ID

    2395

    UniProt

    Q16595

    途径

    Transition Metal Ion Homeostasis, Regulation of Cell Size
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