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Filamin A 抗体

This anti-Filamin A antibody is a 兔 单克隆 antibody detecting Filamin A in WB, IHC, IHC (p), IF (cc) 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6943468
发货至: 中国

Quick Overview for Filamin A 抗体 (ABIN6943468)

抗原

See all Filamin A (FLNA) 抗体
Filamin A (FLNA) (Filamin A, alpha (FLNA))

适用

  • 108
  • 33
  • 22
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  • 1
人, 小鼠, 大鼠

宿主

  • 99
  • 9
  • 1

克隆类型

  • 88
  • 21
单克隆

标记

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  • 2
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This Filamin A antibody is un-conjugated

应用范围

  • 57
  • 35
  • 33
  • 28
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  • 16
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  • 10
  • 7
  • 5
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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)

克隆位点

2G3
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Human Filamin A, C-terminus

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Filamin A (FLNA) (Filamin A, alpha (FLNA))

    别名

    Filamin A

    背景

    Synonyms: Filamin-A, Actin-binding protein 280, Alpha-filamin, Endothelial actin-binding protein, Filamin-1, Non-muscle filamin, FLN-A, ABP-280

    Background: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintainance (By similarity).

    基因ID

    2316

    UniProt

    P21333

    途径

    TCR Signaling, Maintenance of Protein Location
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