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EXOSC5 抗体 (AA 141-235) (AbBy Fluor® 555)

This anti-EXOSC5 antibody is a 兔 多克隆 antibody detecting EXOSC5 in IF (cc) 和 IF (p). Suitable for 小鼠.
产品编号 ABIN6943378
发货至: 中国

Quick Overview for EXOSC5 抗体 (AA 141-235) (AbBy Fluor® 555) (ABIN6943378)

抗原

See all EXOSC5 抗体
EXOSC5 (Exosome Component 5 (EXOSC5))

适用

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  • 1
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小鼠

宿主

  • 27
  • 5

克隆类型

  • 29
  • 3
多克隆

标记

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This EXOSC5 antibody is conjugated to AbBy Fluor® 555

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 10
    • 2
    • 1
    • 1
    • 1
    AA 141-235

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human EXOSC5

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    EXOSC5 (Exosome Component 5 (EXOSC5))

    别名

    EXOSC5

    背景

    Synonyms: Chronic myelogenous leukemia tumor antigen 28, CML28, EXOS5_HUMAN, EXOSC 5, Exosc5, Exosome complex component rrp46, exosome complex exonuclease RRP46, Exosome component 5, exosome component Rrp46, hRrp46p, p12B, Ribosomal RNA processing protein 46, Ribosomal RNA processing protein 46, S. cerevisiae, homolog of, Ribosomal RNA-processing protein 46, RRP41B, RRP46, Rrp46p.

    Background: The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3 to 5 exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3 region. EXOSC5 (Exosome component 5), also known as Exosome complex exonuclease RRP46 and CML28 (Chronic myelogenous leukemia tumor antigen 28), is one of at least eleven components of the exosome complex and is required for processing of 7S pre-RNA to mature 5.8S rRNA. Located in the nucleus, EXOSC5 interacts with both EXOSC1 and EXOSC7. EXOSC5 is exclusively expressed in normal testis, though is found to be highly expressed in many hematopoietic and epithelial tumor cell lines, suggesting that it may be an appropriate target for antigen-specific immunotherapy.

    基因ID

    56915

    UniProt

    Q9NQT4

    途径

    SARS-CoV-2 Protein Interactome
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