Envoplakin-Like 抗体 (AA 101-200) (AbBy Fluor® 594)
Quick Overview for Envoplakin-Like 抗体 (AA 101-200) (AbBy Fluor® 594) (ABIN6943319)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 101-200
-
交叉反应
- 人
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human EVPLL
-
亚型
- IgG
-
-
anti-Envoplakin-Like (EVPLL) (AA 118-146) antibody
EVPLL 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB31164 unconjugated
anti-Envoplakin-Like (EVPLL) (AA 117-146), (Middle Region) antibodyEVPLL 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- Envoplakin-Like (EVPLL)
-
别名
- EVPLL
-
背景
-
Synonyms: Envoplakin like, Envoplakin-like protein, EVPLL, EVPLL_HUMAN,
Background: EVPLL (envoplakin-like protein) is a 301 amino acid protein that belongs to the plakin or cytolinker family. The gene encoding EVPLL maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
-
基因ID
- 645027
-
UniProt
- A8MZ36
抗原
-
