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EN1 抗体 (AA 351-392) (PE)

This anti-EN1 antibody (ABIN6943253) is a Rabbit Polyclonal antibody detecting EN1 in WB, FACS. Suitable for Human, Mouse, Rat.
产品编号 ABIN6943253
发货至: 中国

Quick Overview for EN1 抗体 (AA 351-392) (PE) (ABIN6943253)

抗原

See all EN1 抗体
EN1 (Engrailed Homeobox 1 (EN1))

适用

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人, 小鼠, 大鼠

宿主

  • 37
  • 1

克隆类型

  • 34
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多克隆

标记

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This EN1 antibody is conjugated to PE

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 5
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    • 1
    • 1
    • 1
    AA 351-392

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Sheep,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human EN1/Engrailed 1

    亚型

    IgG
  • 应用备注

    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    EN1 (Engrailed Homeobox 1 (EN1))

    别名

    EN1/Engrailed 1

    背景

    Synonyms: En 1, EN1, Engrailed 1, Engrailed, Engrailed homeobox 1, Engrailed homolog 1, HME1_HUMAN, Homeobox protein en-1, Homeobox protein engrailed 1, Homeobox protein engrailed-1, Hu-En-1, Mo-en.1.

    Background: The engrailed-1 gene, EN1, a murine homolog of the Drosophila homeobox gene engrailed (EN), is required for midbrain and cerebellum development and dorsal/ventral patterning of the limbs as well as apical ectodermal ridge formation. In Drosophila, the EN gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Human EN-1 and EN-2 are homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. Different mutations in the mouse homo-logs, EN-1 and EN-2, produce different developmental defects that frequently are lethal. EN-1 is highly expressed by essentially all dopaminergic neurons in the substantia nigra and ventral tegmentum. EN-1 and EN-2 regulate expres-sion of a-synuclein, a gene that is genetically linked to Parkinson?s disease.

    基因ID

    2019

    UniProt

    Q05925

    途径

    Dopaminergic Neurogenesis
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