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DUSP26 抗体 (AA 111-211) (AbBy Fluor® 647)

This AbBy Fluor® 647-conjugated 兔 多克隆 anti-DUSP26 antibody specifically detects DUSP26 in WB, IF (cc) 和 IF (p). The antibody is reactive with 大鼠 samples.
产品编号 ABIN6943144
发货至: 中国
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Quick Overview for DUSP26 抗体 (AA 111-211) (AbBy Fluor® 647) (ABIN6943144)

抗原

See all DUSP26 抗体
DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))

适用

  • 36
  • 32
  • 8
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
大鼠

宿主

  • 59
  • 1

克隆类型

  • 61
多克隆

标记

  • 19
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DUSP26 antibody is conjugated to AbBy Fluor® 647

应用范围

  • 40
  • 25
  • 25
  • 17
  • 11
  • 10
  • 6
  • 6
  • 6
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 14
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 111-211

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human DUSP26

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))

    别名

    DUSP26

    背景

    Synonyms: DSP-4, Dual specificity phosphatase 26 (putative), Dual specificity phosphatase 26, Dual specificity phosphatase SKRP3, Dual specificity protein phosphatase 26, DUS26_HUMAN, DUSP24, DUSP26, Hypothetical protein FLJ31142, LDP 4, LDP-4, Low molecular mass dual specificity phosphatase 4, Low-molecular-mass dual-specificity phosphatase 4, MAP kinase phosphatase 8, MGC1136, MGC2627, Mitogen activated protein kinase phosphatase 8, Mitogen-activated protein kinase phosphatase 8, MKP-8, MKP8, NATA1, NATA1 protein, Novel amplified gene in thyroid anaplastic cancer, SKRP3.

    Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways, which are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DUSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DUSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP26, also designated LDP4, MKP8, NATA1 and SKRP3, is ubiquitously expressed in brain except in the hippocampus. DUSP26 dephosphorylates p38 thereby inhibiting p38-mediated apoptosis in anaplastic thyroid cancer cells. Downregulation of DUSP26 may also contribute to malignant phenotypes of glioma.

    基因ID

    78986

    UniProt

    Q9BV47
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