DUSP26 抗体 (AA 111-211) (AbBy Fluor® 555)
Quick Overview for DUSP26 抗体 (AA 111-211) (AbBy Fluor® 555) (ABIN6943142)
抗原
See all DUSP26 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 111-211
-
交叉反应
- 大鼠
-
预测反应
- Human,Mouse,Cow,Pig,Horse,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human DUSP26
-
亚型
- IgG
-
-
anti-Dual Specificity Phosphatase 26 (DUSP26) (AA 1-211) antibody
DUSP26 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 26 (DUSP26) (Center) antibodyDUSP26 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 26 (DUSP26) antibodyDUSP26 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 26 (DUSP26) (C-Term) antibodyDUSP26 适用: 人, 大鼠, Hamster, 马, Cow, 猴, 兔, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 26 (DUSP26) (Internal Region) antibodyDUSP26 适用: 人, 大鼠, 小鼠, Hamster, 马, Cow, 猴, 兔, Bat, Pig, 小鸡 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 26 (DUSP26) (Internal Region) antibodyDUSP26 适用: 人, 大鼠, 小鼠, Hamster, 马, Cow, 猴, 兔 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 26 (DUSP26) (AA 1-110) antibodyDUSP26 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))
-
别名
- DUSP26
-
背景
-
Synonyms: DSP-4, Dual specificity phosphatase 26 (putative), Dual specificity phosphatase 26, Dual specificity phosphatase SKRP3, Dual specificity protein phosphatase 26, DUS26_HUMAN, DUSP24, DUSP26, Hypothetical protein FLJ31142, LDP 4, LDP-4, Low molecular mass dual specificity phosphatase 4, Low-molecular-mass dual-specificity phosphatase 4, MAP kinase phosphatase 8, MGC1136, MGC2627, Mitogen activated protein kinase phosphatase 8, Mitogen-activated protein kinase phosphatase 8, MKP-8, MKP8, NATA1, NATA1 protein, Novel amplified gene in thyroid anaplastic cancer, SKRP3.
Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways, which are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DUSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DUSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP26, also designated LDP4, MKP8, NATA1 and SKRP3, is ubiquitously expressed in brain except in the hippocampus. DUSP26 dephosphorylates p38 thereby inhibiting p38-mediated apoptosis in anaplastic thyroid cancer cells. Downregulation of DUSP26 may also contribute to malignant phenotypes of glioma.
-
基因ID
- 78986
-
UniProt
- Q9BV47
抗原
-
